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Cardiac metastasis of hepatocellular carcinoma in a young non-cirrhotic patient, to the left ventricle

Ebru Tastekin, Ufuk Usta, Turan Ege, Gokhan Kazindir, Ali Kemal Kutlu


Hepatocellular carcinoma (HCC) is the most common primary tumor of the liver.1,2 The most common extrahepatic metastatic sites are lung, abdominal lymph nodes and bone, while its cardiac metastasis is rare.2,3 Metastasis of HCC into the cardiac cavity is mostly caused by direct tumor invasion of vena cava inferior with continuous extension into the right cardiac cavity.4,5 Right heart metastasis without invasion of inferior vena cava, which may be caused by hematogenous spread of cancer cells, is rarely reported.6,7 This paper announces an unusual case of isolated involvement of left ventricle (LV) together with myocardial invasion of HCC. Our patient is known to be the first case with isolated HCC metastasis to the left ventricle. Strikingly, the patient was young and non-cirrhotic with negative serum HBsAg, and anti-HCV results.

Key words. Hepatocellular carcinoma, Metastasis, Left ventricle metastasis, Cardiac tumors

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The Official Journal of the Mexican Association of Hepatology, the Latin-American Association for the Study of the Liver and the Canadian Association for the Study of the Liver

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